In a cross-sectional study of 701 individuals ages 50-89 years to assess the prevalence and severity of Restless Legs Syndrome (RLS), investigators report that the serum iron, transferrin and ferritin were similar in RLS and non-RLS patients, but the soluble transferrin receptor (sTR) concentrations were higher in subjects with and without RLS. Female sex and high sTR independently predicted the risk of RLS. A high sTr indicates increased iron turnover.
Neurology. 2005 Jun 14;64(11):1920-4.
Posted on Wed, October 21, 2009
by David Garrison