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Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in TH


Iron loading increases cholesterol accumulation and macrophage scavenger receptor I expression in TH

Loading of mononuclear phagocytes with iron leads to oxidization of LDL, increased cellular cholesterol accumulation and scavenger receptor expression, and supports the hypothesis that increased macrophage iron levels promote atherogenesis.

Metabolism. 2005 Apr;54(4):453-9.

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